SNP Array − A Powerful Platform to Accelerate Genetic Studies and Breeding
نویسندگان
چکیده
منابع مشابه
Single-copy gene based 50 K SNP chip for genetic studies and molecular breeding in rice
Single nucleotide polymorphism (SNP) is the most abundant DNA sequence variation present in plant genomes. Here, we report the design and validation of a unique genic-SNP genotyping chip for genetic and evolutionary studies as well as molecular breeding applications in rice. The chip incorporates 50,051 SNPs from 18,980 different genes spanning 12 rice chromosomes, including 3,710 single-copy (...
متن کاملTitle: Powerful SNP Set Analysis for Case-Control Genome Wide Association Studies Running Title: Powerful SNP Set Analysis
Genome wide association studies (GWAS) have emerged as popular tools for identifying genetic variants that are associated with disease risk. Standard analysis of a case-control GWAS involves assessing the association between each individual genotyped SNP and disease risk. However, this approach suffers from limited reproducibility and difficulties in detecting multi-SNP and epistatic effects. A...
متن کاملDevelopment and Evaluation of a 9K SNP Array for Peach by Internationally Coordinated SNP Detection and Validation in Breeding Germplasm
Although a large number of single nucleotide polymorphism (SNP) markers covering the entire genome are needed to enable molecular breeding efforts such as genome wide association studies, fine mapping, genomic selection and marker-assisted selection in peach [Prunus persica (L.) Batsch] and related Prunus species, only a limited number of genetic markers, including simple sequence repeats (SSRs...
متن کاملA powerful and robust test in genetic association studies.
There are several well-known single SNP tests presented in the literature for detecting gene-disease association signals. Having in place an efficient and robust testing process across all genetic models would allow a more comprehensive approach to analysis. Although some studies have shown that it is possible to construct such a test when the variants are common and the genetic model satisfies...
متن کاملHigh-Throughput SNP Genotyping to Accelerate Crop Improvement
Recent advances in next-generation sequencing (NGS) and single nucleotide polymorphism (SNP) genotyping promise to greatly accelerate crop improvement if properly deployed. High-throughput SNP genotyping offers a number of advantages over previous marker systems, including an abundance of markers, rapid processing of large populations, a variety of genotyping systems to meet different needs, an...
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ژورنال
عنوان ژورنال: Journal of Plant Biochemistry & Physiology
سال: 2014
ISSN: 2329-9029
DOI: 10.4172/2329-9029.1000e119